Anti-CHMP5 antibodies are used in the immunodetection of the protein charged multivesicular body protein 5. In humans, the canonical protein has a reported length of 219 amino acid residues and a mass of 24.6 kDa. Its subcellular localization is in the membrane and cytoplasm. Alternative splicing is reported to yield 2 different isoforms for this protein. A member of a the SNF7 protein family, CHMP5 is a suspected peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. Synonyms for this target antigen include CGI-34, HSPC177, PNAS-2, SNF7DC2, Vps60, SNF7 domain containing 2, SNF7 domain-containing protein 2, and C9orf83.