Anti-ADSL antibodies are used in the immunodetection of the protein adenylosuccinate lyase. In humans, the canonical protein has a reported length of 484 amino acid residues and a mass of 54.9 kDa. Up to 2 different isoforms have been reported for this protein. It is ubiquitously expressed across many tissue types. A member of the Lyase 1 protein family, ADSL is known to catalyze two non-sequential steps in de novo AMP synthesis: converts (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate (SAICAR) to fumarate plus 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide, and thereby also contributes to de novo IMP synthesis, and converts succinyladenosine monophosphate (SAMP) to AMP and fumarate. Synonyms for this target antigen include ASASE, ASL, adenylosuccinase, and AMPS. ADSL gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of ADSL antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA, Immunofluorescence, and Immunohistochemistry are also common applications.