Anti-IL-1F9 antibodies are used in antigen-specific immunodetection in biological samples. The target IL-1F9 is a known alias name of the protein interleukin 36 gamma, encoded by the IL36G gene in humans. This 169-amino acid residue protein is a reported to be a cytokine that binds to and signals through the IL1RL2/IL-36R receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells. It is localized to the cytoplasm and is secreted of the cell and features cleaved post-translational modifications. In terms of tissue expression, it is reported to be highly expressed in tissues containing epithelial cells: skin, lung, stomach and esophagus.