Anti-IKK2 antibodies are used in antigen-specific immunodetection in biological samples. The target IKK2 is a known alias name of the protein inhibitor of nuclear factor kappa B kinase subunit beta, encoded by the IKBKB gene in humans. This 756-amino acid residue protein is reported to be a serine kinase that plays an essential role in the NF-kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. It is localized to the nucleus and cytoplasm of the cell and features ubiquitinated, acetylated and phosphorylated post-translational modifications. In terms of tissue expression, it is reported to be highly expressed in the heart, placenta, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, testis and peripheral blood. Other synonyms for IKK2 include IKK-beta and IKKB. ELISA is the most common application for the IKK2 antibodies listed below. Western Blot and Immunohistochemistry are also common applications.