Anti-Neuropilin 2 antibodies are used in the immunodetection of the protein encoded by the NRP2 gene. In humans, the canonical protein has a reported length of 931 amino acid residues and a mass of 104.8 kDa. Its subcellular localization is in the membrane and is also secreted. Alternative splicing is reported to yield 6 different isoforms for this protein. A member of the Neuropilin protein family, it is a high affinity receptor for semaphorins 3C, 3F, VEGF-165 and VEGF-145 isoforms of VEGF, and the PLGF-2 isoform of PGF; (Microbial infection) Acts as a receptor for human cytomegalovirus pentamer-dependent entry in epithelial and endothelial cells. Post-translational modifications have been described, including glycosylation. Other names for this target antigen include NPN2, PRO2714, VEGF165R2, neuropilin-2a(17), neuropilin-2a(22), and NP2.