Neuropilin-2 (D39A5) XP ® Rabbit mAb 3366S from Cell Signaling Technology

Product Specs
ItemNeuropilin-2 (D39A5) XP ® Rabbit mAb
CompanyCell Signaling Technology
Price $371.00 Inquire
Catalog Number3366S
ClonalityMonoclonal
NCBI Full Gene Nameneuropilin 2
ApplicationsWB, IF, IHC-p, IP
ReactivityMs, Rt
Research AreaNeuroscience
IsotypeIgG
CloneD39A5
Molecular Weight130
NCBI Gene Aliases1110048P06Rik, Np-2, Np2, Npn-2, Npn2
HostRabbit
TargetNeuropilin2 mouse
Quantity100 µl

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Cell Signaling Technology

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Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

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Website: http://www.cellsignal.com/

Website: Technical Support

(1) Characterization of mouse melanocytes reveals ultrastructural and immunological insights into the inner ear functionCommunications BiologyJanuary 26, 2026Jing Cai, Lei Xu, Yongdong Song, Aizhen Zhang, Zheng Li, Ligang Kong, Kaifan Xu, Yu Jin, Siyue Wang, Junze Lu, et al.(1:500; Ab5076, Abcam), Melan-A (1:200; nbp-30151, Novus), Met (1:50; Ab216330, Abcam), Nrp2 (1:50; 3366, Cell Signaling), and Kir4.1 (1:100; 312844, Abcam). The antibodies were diluted and incubated overnight

(2) Hypoxic migrasomes drive colorectal cancer liver metastasis by mediating CD5L+ macrophage efferocytosis via NRP2/PROX1 axisJ Transl MedDecember 8, 2025Yuqi Luo, Yiwen Huang, Yaoxing Huang, Longzhen Chenprimary antibodies, CD5L (1:500, 17224-1-AP, Proteintech), CD163 (1:200, ab182422, Abcam), NRP2 (1:250, #3366, CST), PROX1(1:250, sc-81983, Santa cruz), MERTK (200 µg/mL, sc-365499, Santa Cruz). After washing off

(3) Endothelial cells-derived SEMA3G suppresses glioblastoma stem cells by inducing c-Myc degradationCell death and differentiationDecember 1, 2025Min PX, Feng LL, Zhang YX, Jiang CC, Zhang HZ, Chen Y, Fukunaga K, Liu F, Zhang YJ, Sasaki T, et al.were blocked with 1% BSA at room temperature for 1 h, incubated with primary antibodies against NRP2 (#3366, Cell Signaling Technology, MA, USA) overnight, and then with species-matched secondary antibodies conjugated

(4) MBsNRP2-based ultrasound molecular imaging for early diagnosis of castration-resistant prostate cancerBMC CancerApril 24, 2025Na Wang, Xinzhi Xu, Yizhe Zhong, Yujie Wan, Ruixia Hong, Qizhi Wang, Jia Tang, Jiaqi Gong, Hang Zhou, Fang LiEndothelial cells were labeled with anti-mouse CD31 antibody (3528, CST) and anti-rabbit Neuropilin- 2 antibody (3366, CST), followed by secondary Alexa Fluor 647-coupled goat anti-mouse IgG (4410, CST) and Alexa Fluor

(5) Semaphorin 3F inhibits breast cancer metastasis by regulating the Akt-mTOR and TGFβ signaling pathways via neuropilin-2Scientific reportsMarch 3, 2025Nakayama H, Murakami A, Nishida-Fukuda H, Fukuda S, Matsugi E, Nakahara M, Kusumoto C, Kamei Y, Higashiyama S.anti-PTEN antibody (#9188); rabbit monoclonal anti-vimentin antibody (#5741); rabbit monoclonal anti-NRP2 (#3366) were all purchased from Cell Signaling Technology. Mouse monoclonal anti-NRP1 antibody (A-12, sc-5307)

(6) Lyve1‐Driven NrasQ61R Causes Edema, Enlarged Lymphatic Vessels, and Hepatic Vascular Defects in Embryonic MicePediatric Blood & CancerMarch 1, 2025C. Griffin McDaniel, Dermot Fox, Patricia Pastura, Sara Alharbi, Stacey S. Huppert, Timothy D. Le Le Crasserum. The next day, samples were incubated overnight in primary antibody for neuropilin-2 (1:500, 3366; Cell Signaling) diluted in PBST + 1% bovine serum albumin (BSA). Neuropilin-2 is expressed by lymphatic

(7) Analysis of PD1, LAG3, TIGIT, and TIM3 expression in human lung adenocarcinoma reveals a 25-gene signature predicting immunotherapy responseCell Reports MedicineDecember 17, 2024Jean-Philippe Guégan, Florent Peyraud, Bérengère Dadone-Montaudie, Diego Teyssonneau, Lola-Jade Palmieri, Emma Clot, Sophie Cousin, Guilhem Roubaud, Mathilde Cabart, Laura Leroy, et al.SP52,Roche,05986818001 anti-TIM-3 – Clone D5D5R™,Cell Signaling Technology,45208 anti-LAG-3 – Clone EP294,BioSB,BSB 3366 anti-CD8 – Clone C8/144B,Agilent Dako,GA62361-2 anti-TIGIT – Clone BLR047F,Abcam,RRID:AB_2943164 DISCOVERY

(8) Semaphorin Receptors Antagonize Wnt Signaling Through Beta-Catenin DegradationbioRxiv : the preprint server for biologyMay 29, 2024Hoard TM, Liu K, Cadigan KM, Giger RJ, Allen BL.Bank,E7 NRP1 (Goat IgG),"1:200 (IF)1:2,000 (WB)",R&D Systems,AF566 NRP2 (Rabbit IgG),1:500,Cell Signaling,3366S FLAG (Mouse IgG1),1:500,Sigma,F3165 MYC (Rabbit IgG),"1:5,000",Bethyl Labs,A190-105A HA (Mouse IgG2b),"1:1,000

(9) A proteomics approach to isolating neuropilin-dependent α5 integrin trafficking pathways: neuropilin 1 and 2 co-traffic α5 integrin through endosomal p120RasGAP to promote polarised fibronectin fibrillogenesis in endothelial cellsCommunications biologyMay 24, 2024Benwell CJ, Johnson RT, Taylor JAGE, Lambert J, Robinson SD.1:2000), NRP1 (R&D: AF566, RRID: AB_355445, 1:100), NRP2 (SCB: sc-13117, RRID: AB_628044, 1:50; CST: 3366, RRID: AB_2155250, 1:1000), Clathrin heavy chain-1 (Ab21679, RRID: AB_2083165, 1:100), Dynamin-2 (Ab3457,

(10) Hyperactive KRAS/MAPK signaling disrupts normal lymphatic vessel architecture and functionFrontiers in Cell and Developmental BiologySeptember 25, 2023Lorenzo M. Fernandes, Jeffrey Tresemer, Jing Zhang, Jonathan J. Rios, Joshua P. Scallan, Michael T. Dellinger1:50), rabbit anti-Prox1 (AngioBio, 11-002; dilution 1:1000), rabbit anti-neuropilin-2 (Cell Signaling, 3366; dilution 1:500), rabbit anti-Runx1 (Abcam, ab92336; dilution 1:1000), and rabbit anti-KRASG12D (Cell Signaling

(11) Palmitoylation regulates neuropilin-2 localization and function in cortical neurons and conveys specificity to semaphorin signaling via palmitoyl acyltransferasesElifeApril 3, 2023Eleftheria Koropouli, Qiang Wang, Rebeca Mejías, Randal Hand, Tao Wang, David D Ginty, Alex L Kolodkinmonoclonal, Abcam, EP892Y, Cat no. ab52649); neuropilin-2 (Nrp2) (rabbit polyclonal, Cell Signaling, Cat no. 3366S); Nrp2 (goat polyclonal, Research & Development, Cat no. AF2215); PlexA3 (rabbit polyclonal, Abcam,

(12) Single-cell transcriptomic analysis reveals diversity within mammalian spinal motor neuronsNature communicationsJanuary 3, 2023Liau ES, Jin S, Chen YC, Liu WS, Calon M, Nedelec S, Nie Q, Chen JA.(1:500 Novus Cat# AF7006, RRID:AB_10972102); rabbit anti-Nrp2 (1:200 Cell Signaling Technology Cat# 3366, RRID:AB_2155250). Guinea pig anti-Foxp1 (1:320000), anti-Isl1 (1:10000, cat# CU1277, RRID:AB_2631974),

(13) Guidance landscapes unveiled by quantitative proteomics to control reinnervation in adult visual systemNature communicationsOctober 13, 2022Vilallongue N, Schaeffer J, Hesse AM, Delpech C, Blot B, Paccard A, Plissonnier E, Excoffier B, Couté Y, Belin S, et al.Cell signalling Technology, #3725), anti-Neuropilin-2 (1:1000, Rabbit, Cell signalling Technology, #3366), anti-Plexin-A4 (1:1000, Rabbit, Cell signalling Technology, #3816), anti-Ephrin-B3 (1:500, Rabbit,

(14) Differential proteomic analysis of mouse cerebrums with high-fat diet (HFD)-induced hyperlipidemiaPeerJAugust 3, 2022Changming Chen, Meiling Wen, Caixia Wang, Zhongwen Yuan, Ya Jin(rabbit monoclonal, #137043; Abcam, Cambridge, UK), anti-Nrp2 antibody (rabbit monoclonal, Product #3366; Cell Signaling Tech., Danvers, MA, USA) and anti-GAPDH (rabbit monoclonal, Product #2118S; Cell Signaling

(15) Integrated single-cell analyses decode the developmental landscape of the human fetal spineiScienceJuly 15, 2022Yu H, Tang D, Wu H, Li C, Lu Y, He F, Zhang X, Yang Y, Shi W, Hu W, et al.anti-MATN3 (#ab238893, Abcam), anti-CD74 (#77274, CST), anti-APP (#29765, CST), anti- Neuropilin-2 (#3366, CST), anti-HAPLN1 (#181997, Abcam), anti-SEMA3C (#MAB1728-SP, R&D), anti-EPYC (#NBP2-33445, Novus),

(16) Inactivation of EGLN3 hydroxylase facilitates Erk3 degradation via autophagy and impedes lung cancer growthOncogeneMarch 1, 2022Jin Y, Pan Y, Zheng S, Liu Y, Xu J, Peng Y, Zhang Z, Wang Y, Xiong Y, Xu L, et al.(Yeasen, 30902ES60), anti-NRP1 (Cell Signaling Technology, #3725), anti-NRP2 (Cell Signaling Technology, #3366), anti-EGLN3 (Novus, NB100–303), anti-Erk3 (Santa Cruz Biotechnology, sc-365234), anti-arginase1 (Cell Signaling Technology

(17) Polysialic acid and Siglec-E orchestrate negative feedback regulation of microglia activationCellular and molecular life sciences : CMLSFebruary 1, 2021Thiesler H, Beimdiek J, Hildebrandt H.cat. #PRB‐114C, 1:10,000), NRP2‐specific rabbit mAb D39A5 (Cell Signaling, Beverly, MA, USA, cat. #3366S, 1:1000), EEA1 (early endosomal antigen 1)-specific antibody rabbit pAb (Santa Cruz Biotechnology, Santa

(18) Atypical cadherin FAT4 orchestrates lymphatic endothelial cell polarity in response to flowThe Journal of clinical investigationJune 1, 2020Betterman KL, Sutton DL, Secker GA, Kazenwadel J, Oszmiana A, Lim L, Miura N, Sorokin L, Hogan BM, Kahn ML, et al.anti–mouse laminin α5 (58), goat anti–human neuropilin 2 (AF2215; R&D Systems), rabbit neuropilin 2 XP (3366; Cell Signaling Technology), rat anti-endomucin (V.7C7, sc-65495; Santa Cruz Biotechnology), rat anti–mouse

(19) Automatic Hierarchical Classification of Kelps Using Deep Residual FeaturesSensors (Basel)January 13, 2020Ammar Mahmood, Ana Giraldo Ospina, Mohammed Bennamoun, Senjian An, Ferdous Sohel, Farid Boussaid, Renae Hovey, Robert B. Fisher, Gary A. KendrickID 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 483 20 20 1 2 7 0 3 7 44 1 15 2 2 7 265 24 887 46 7 50 1 0 1 1 1 10 47 15 102 0 2644 37 66 1 112762 2419 1733 1 2839 6744 29948 1252 2 9 1 4 2 285 3 1177 52 16571 137 24637 2 1505 294 13 0 0 0 0 3 0 1 19 1 3 0 2 3 38 1 355 2 3 8 0 2 0 1 0 7 2 1 31 3 2561 0 113 1 43014 1124 173 1 586 1300 11686 2073 0 0 0 0 0 87 1 2391 6 3366 0 4846 0 163 BRYH BRYS CB CBBF CBBH CBOT CNHYC CNHYD CSBL CSBR CSBRBL CSCOLBL CSCOR CSCORBL CSDBL CSE CSEBL CSF CSFBL CSM CSSO CSSOBL CSST CSSUBL CST CSTBL EF ESC ESS FELR MAAG MAAR MACAU MAECB MAECG MAECK

(20) NRP2 as an Emerging Angiogenic Player; Promoting Endothelial Cell Adhesion and Migration by Regulating Recycling of α5 IntegrinFrontiers in cell and developmental biologyJanuary 1, 2020Alghamdi AAA, Benwell CJ, Atkinson SJ, Lambert J, Johnson RT, Robinson SD.immunoprecipitated by incubation with protein-G Dynabeads (Invitrogen) coupled to a rabbit anti-NRP2 antibody (clone 3366, Cell Signaling Technology) on a rotator overnight at 4◦ C. Immunoprecipitated complexes were then washed

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Neuropilin-2 (D39A5) XP ® Rabbit mAb

Neuropilin-2 (D39A5) XP ® Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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Neuropilin-2 (D39A5) XP ® Rabbit mAb from Cell Signaling Technology

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