Anti-TGFB1 antibodies are used in the immunodetection of the protein transforming growth factor beta 1. In humans, the canonical protein has a reported length of 390 amino acid residues and a mass of 44.3 kDa. Its subcellular localization is in the extracellular matrix and is secreted. It is reported to be highly expressed in bone. A member of the TGF-beta protein family, TGFB1 is known to be involved with cell migration and chondrocyte differentiation. Post-translational modifications have been described, including N-glycosylation and protein cleavage. TGFB1 is also used as a cellular marker for characterizing myeloid-derived suppressor cells. Synonyms for this target antigen include DPD1, IBDIMDE, LAP, TGF-beta1, TGFB, TGFbeta, transforming growth factor beta-1 proprotein, and CED. TGFB1 gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species.