Anti-PMS2 antibodies are used in the immunodetection of the protein PMS1 homolog 2, mismatch repair system component. In humans, the canonical protein has a reported length of 862 amino acid residues and a mass of 95.8 kDa. Its subcellular localization is in the nucleus. Up to 4 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. A member of the DNA mismatch repair MutL/HexB protein family, Pms2 is a known component of the post-replicative DNA mismatch repair system (MMR). Synonyms for this target antigen include LYNCH4, MLH4, MMRCS4, PMS2CL, PMSL2, mismatch repair endonuclease PMS2, DNA mismatch repair protein PMS2, and HNPCC4. PMS2 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of Pms2 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. Immunofluorescence and Immunohistochemistry are also common applications.