Anti-PDPK1 antibodies are used in the immunodetection of the protein 3-phosphoinositide dependent protein kinase 1. In humans, the canonical protein has a reported length of 556 amino acid residues and a mass of 63.2 kDa. Its subcellular localization is in the cell membrane, nucleus, and cytoplasm. Up to 5 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. A member of the AGC Ser/Thr protein kinase protein family, PDPK1 is known to be a serine/threonine kinase that acts as a master kinase, phosphorylating and activating a subgroup of the AGC family of protein kinases. Synonyms for this target antigen include PDPK2, PDPK2P, PRO0461, 3-phosphoinositide-dependent protein kinase 2 pseudogene, PkB kinase like gene 1, and PDK1. PDPK1 gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. Over 590 citations in the literature describe the use of PDPK1 antibodies in research. Western Blot is a widely used application for these antibodies. Immunofluorescence and Immunohistochemistry are also common applications.