Anti-LCP2 antibodies are used in the immunodetection of the protein lymphocyte cytosolic protein 2. In humans, the canonical protein has a reported length of 533 amino acid residues and a mass of 60.2 kDa. Its subcellular localization is in the cytoplasm. It is reported to be highly expressed in spleen, thymus and peripheral blood leukocytes. LCP2 is known to be involved in T-cell antigen receptor mediated signaling. Post-translational modifications have been described, including phosphorylation.
The LCP2 marker can be used to identify CD8?a Thymocytes.* Synonyms for this target antigen include SLP-76, SLP76, 76 kDa tyrosine phosphoprotein, SH2 domain-containing leukocyte protein of 76 kDa, SLP-76 tyrosine phosphoprotein, and IMD81. LCP2 gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. Over 100 citations in the literature describe the use of LCP2 antibodies in research. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.
*HuBMAP Human Reference Atlas v1.4