Anti-HTR2B antibodies are used in the immunodetection of the protein 5-hydroxytryptamine receptor 2B. In humans, the canonical protein has a reported length of 481 amino acid residues and a mass of 54.3 kDa. Its subcellular localization is in the cell membrane. It is ubiquitously expressed across many tissue types. A member of the G-protein coupled receptor 1 protein family, HTR2B is known to be involved with chemical synaptic transmission. Post-translational modifications have been described, including glycosylation. Synonyms for this target antigen include 5-HT-2B, 5-HT2B, 5-HT 2B receptor, 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled, 5-hydroxytryptamine 2B receptor, and 5-HT(2B). HTR2B gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of HTR2B antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA, Immunofluorescence, and Immunohistochemistry are also common applications.