Anti-GRB2 antibodies are used in the immunodetection of the protein growth factor receptor bound protein 2. In humans, the canonical protein has a reported length of 217 amino acid residues and a mass of 25.2 kDa. Its subcellular localization is in the nucleus, golgi, and cytoplasm. Alternative splicing is reported to yield 2 different isoforms for this protein. A member of a the GRB2/sem-5/DRK protein family, GRB2 is a reported adaptor protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Synonyms for this target antigen include EGFRBP-GRB2, Grb3-3, MST084, MSTP084, NCKAP2, HT027, SH2/SH3 adapter GRB2, and ASH.