Anti-FADD antibodies are used in the immunodetection of the protein Fas associated via death domain. In humans, the canonical protein has a reported length of 208 amino acid residues and a mass of 23.3 kDa. It is reported to be expressed in a wide variety of tissues, except for peripheral blood mononuclear leukocytes. FADD is known to be involved with the apoptotic pathway and viral immune response. Post-translational modifications have been described, including glycosylation. The FADD gene has been associated with the disease, Infections. Synonyms for this target antigen include IMD90, MORT1, FAS-associated death domain protein, Fas (TNFRSF6)-associated via death domain, and GIG3. FADD gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Over 200 citations in the literature describe the use of FADD antibodies in research. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.