Anti-SP4 antibodies are used in the immunodetection of the protein Sp4 transcription factor. In humans, the canonical protein has a reported length of 784 amino acid residues and a mass of 82 kDa. Its subcellular localization is in the nucleus. It is notably expressed in the brain. A member of the Sp1 C2H2-type zinc-finger protein family, Sp4 is known to bind to GT and GC boxes promoters elements. Synonyms for this target antigen include SPR-1, transcription factor Sp4, and HF1B. SP4 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some Sp4 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. Immunocytochemistry, Immunofluorescence, and Immunohistochemistry are also common applications.