Anti-COPI coat complex subunit beta 1 antibodies are used for the immunodetection of the protein encoded by the COPB1 gene. In humans, the canonical protein has a reported length of 953 amino acid residues and a mass of 107.1 kDa. Its subcellular localization is in the cell membrane, cytoplasmic vesicles, ER, Golgi, and cytoplasm. It is noted to be involved in Golgi transport and intracellular protein transport. Post-translational modifications have been described, including protein cleavage. The gene encoding this protein is implicated in Baralle-Macken syndrome. Other names for this target antigen include COPB, coatomer subunit beta, beta coat protein, beta-cop, coatomer protein complex subunit beta 1, and BARMACS. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.