Anti-WASP actin nucleation promoting factor antibodies are used for the immunodetection of the protein encoded by the WAS gene. In humans, the canonical protein has a reported length of 502 amino acid residues and a mass of 52.9 kDa. Its subcellular localization is in the nucleus and cytoplasm. It is reported to be highly expressed in the thymus. It is noted to be involved in epidermis development. Post-translational modifications have been described, including phosphorylation. The gene encoding this protein is implicated in Wiskott-Aldrich syndrome. Other names for this target antigen include SCNX, THC, THC1, WASP, WASPA, actin nucleation-promoting factor WAS, eczema-thrombocytopenia, and IMD2. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish and chimpanzee species.