Anti-CEA cell adhesion molecule 5 antibodies are used for the immunodetection of the protein encoded by the CEACAM5 gene. In humans, the canonical protein has a reported length of 702 amino acid residues and a mass of 76.8 kDa. Its subcellular localization is in the cell membrane. Alternative splicing is reported to yield 2 different isoforms for this protein. It is reported to be expressed in columnar epithelial and goblet cells of the colon. A member of the CEA protein family, it is known to be involved with the apoptotic pathway and cell adhesion. Post-translational modifications have been described, including glycosylation. Other names for this target antigen include CD66e and CEA. Gene orthologs have been identified in the mouse and chimpanzee species.