Anti-EPRS1 antibodies are used in the immunodetection of the protein glutamyl-prolyl-tRNA synthetase 1. In humans, the canonical protein has a reported length of 1512 amino acid residues and a mass of 170.6 kDa. Its subcellular localization is in the membrane and cytoplasm. It is notably widely expressed in many tissue types. A member of the Class-I aminoacyl-tRNA synthetase protein family, EPRS1 is known to be involved with insulin signaling pathways and the assembly of protein complexes. Post-translational modifications have been described, including phosphorylation. The EPRS1 gene has been associated with the disease, Leukodystrophy. Synonyms for this target antigen include EPRS, GLUPRORS, HLD15, PARS, PIG32, QARS, QPRS, and EARS. EPRS1 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.