Anti-RNF227 antibodies are used in the immunodetection of the protein ring finger protein 227. In humans, the canonical protein has a reported length of 190 amino acid residues and a mass of 21 kDa. RNF227 is known to be involved with protein ubiquitination. Synonyms for this target antigen include long intergenic non-protein coding RNA 2581. RNF227 gene orthologs have been reported in the rat, bovine, frog species.