Anti-IRAG2 antibodies are used in the immunodetection of the protein inositol 1,4,5-triphosphate receptor associated 2. In humans, the canonical protein has a reported length of 555 amino acid residues and a mass of 62.1 kDa. Up to 2 different isoforms have been reported for this protein. It is notably expressed at high levels in pre B-cells, mature B-cells and pre T-cells. A member of the IRAG2 protein family, IRAG2 is reported to play a role in the delivery of peptides to major histocompatibility complex (MHC) class I molecules; this occurs in a transporter associated with antigen processing (TAP)-independent manner. Post-translational modifications have been described, including protein cleavage. Synonyms for this target antigen include LRMP, lymphoid restricted membrane protein, protein Jaw1, and JAW1. IRAG2 gene orthologs have been reported in the mouse, rat, bovine, chimpanzee and chicken species.