Anti-EDN2 antibodies are used in the immunodetection of the protein endothelin 2. In humans, the canonical protein has a reported length of 178 amino acid residues and a mass of 20 kDa. It has been described to be a secreted protein. It is reported to be expressed in the lung, but not in the placental stem villi vessels or cultured placental villi smooth muscle cells. A member of the Endothelin/sarafotoxin protein family, EDN2 is known to be involved with angiogenesis and receptor-mediated signaling pathways. Synonyms for this target antigen include ET2, PPET2, preproendothelin 2, and ET-2. EDN2 gene orthologs have been reported in the mouse, rat, bovine, chimpanzee and chicken species. Some EDN2 antibodies may have been used in research and have associated citations. ELISA is a widely used application for these antibodies. Western Blot and Immunohistochemistry are also common applications.