Anti-ARRB1 antibodies are used in the immunodetection of the protein arrestin beta 1. In humans, the canonical protein has a reported length of 418 amino acid residues and a mass of 47.1 kDa. Its subcellular localization is in the cell membrane, nucleus, cytoplasmic vesicles, and cytoplasm. Up to 2 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. A member of the Arrestin protein family, ARRB1 is reported to function in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. Synonyms for this target antigen include ARR1, beta-arrestin-1, arrestin 2, non-visual arrestin-2, and ARB1. ARRB1 gene orthologs have been reported in the mouse, rat, bovine, chimpanzee and chicken species. Over 120 citations in the literature describe the use of ARRB1 antibodies in research. Western Blot is a widely used application for these antibodies. ELISA, Immunofluorescence, and Immunohistochemistry are also common applications.