Anti-RHEX antibodies are used in the immunodetection of the protein regulator of hemoglobinization and erythroid cell expansion. In humans, the canonical protein has a reported length of 172 amino acid residues and a mass of 19.4 kDa. Its subcellular localization is in the cell membrane. It is reported to be expressed in the proerythroblasts. RHEX is known to act as a signaling transduction factor of the EPO-EPOR signaling pathway promoting erythroid cell differentiation. Post-translational modifications have been described, including phosphorylation. Synonyms for this target antigen include regulator of human erythroid cell expansion protein, uncharacterized protein C1orf186, and regulator of hemoglobinization and erythroid cell expansion protein. RHEX gene orthologs have been reported in the bovine, chimpanzee and chicken species. Western Blot is the most common application for the RHEX antibodies listed below. Immunofluorescence and Immunohistochemistry are also common applications.