Anti-NOTCH2NLA antibodies are used in the immunodetection of the protein notch 2 N-terminal like A. In humans, the canonical protein has a reported length of 236 amino acid residues and a mass of 25.8 kDa. Its subcellular localization is in the cytoplasm and is secreted. Up to 3 different isoforms have been reported for this protein. It is reported to be widely expressed with higher levels in leukocytes and lymph nodes. A member of the NOTCH protein family, NOTCH2NLA is reported to be a human-specific protein that promotes neural progenitor proliferation and evolutionary expansion of the brain neocortex by regulating the Notch signaling pathway. Post-translational modifications have been described, including protein cleavage and glycosylation. Synonyms for this target antigen include notch homolog 2 N-terminal-like protein A and Notch homolog 2 N-terminal like protein. Some NOTCH2NLA antibodies may have been used in research and have associated citations. These antibodies are most commonly used in Western Blot experiments, among other applications.