Anti-BRF2 antibodies are used in the immunodetection of the protein BRF2 RNA polymerase III transcription initiation factor subunit. In humans, the canonical protein has a reported length of 419 amino acid residues and a mass of 46.5 kDa. Its subcellular localization is in the nucleus. Up to 2 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. A member of the TFIIB protein family, BRF2 is reported to be a general activator of RNA polymerase III transcription. Synonyms for this target antigen include TFIIIB50, transcription factor IIIB 50 kDa subunit, B-related factor 2, BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit, and BRFU. BRF2 gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. A number of BRF2 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. In addition, ELISA is also a common application.