Anti-Histone Deacetylase 4 antibodies are used for the immunodetection of the protein encoded by the HDAC4 gene. In humans, the canonical protein has a reported length of 1084 amino acid residues and a mass of 119 kDa. Its subcellular localization is in the nucleus and cytoplasm. Alternative splicing is reported to yield 2 different isoforms for this protein. It is ubiquitously expressed across many tissue types. A member of the Histone deacetylase protein family, it is known to be important for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Other names for this target antigen include BDMR, HA6116, HD4, HDAC-A, HDACA, NEDCHF, NEDCHID, and AHO3. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Over 420 citations in the literature describe the use of Histone Deacetylase 4 antibodies in research. Western Blot is a widely used application for these antibodies. Immunofluorescence and Immunohistochemistry are also common applications.