HDAC4 (D15C3) Rabbit mAb 7628S from Cell Signaling Technology

Product Specs
ItemHDAC4 (D15C3) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number7628S
Quantity100 µl
ApplicationsW, IP
ReactivityH, M, R, Mk
TargetHDAC4
IsotypeIgG
HostRabbit
NCBI Gene AliasesAHO3, BDMR, HA6116, HD4, HDAC-4, HDAC-A, HDACA, NEDCHF, NEDCHID
NCBI Full Gene Namehistone deacetylase 4
CloneD15C3
Molecular Weight140
ClonalityMonoclonal
Research AreaChromatin Regulation / Nuclear Function

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Cell Signaling Technology

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Phone: 978-867-2388
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Website: http://www.cellsignal.com/

Website: Technical Support

(1) Upregulated astrocytic HDAC7 induces depression-like disorders via deacetylating PINK1 and inhibiting mitophagyJournal of NeuroinflammationNovember 24, 2025Rui-zhu Yue, Xing Guo, Cheng-jia Li, Li-juan Wu, Yu-tong Liu, Juan Hu, Bing-kang Yan, Hai-tong Lin, Ying-ling Tang, Wei-ming Yan, et al.Antibody,Catalog,Source,Dilution Acetylated-lysine,9441S,CST,WB: 1:1000 HDAC4,7628S,CST,WB: 1:1000 HDAC5,20458S,CST,WB: 1:1000 HDAC7,H2662,Sigma,WB: 1:1000 HDAC9,AB109446,Abcam,WB:

(2) Targeting Intratumoral Copper Inhibits Tumor Progression via p62-Mediated EZH2 Degradation and Potentiates Anti-PD-1 Immunotherapy in Oral Squamous Cell CarcinomaAdvanced science (Weinheim, Baden-Wurttemberg, Germany)October 1, 2025Lin X, Chen W, Li B, Zhao Z, Yu Z, Zhao XY, Zhou X, Feng Z, Lin C, Cao W.1:1000, RRID: AB_2 881 417), HDAC1 (#5356, CST, USA, dilution 1:1000, RRID: AB_10 612 242), HDAC4 (#7628, CST, USA, dilution 1:1000, RRID: AB_10 860 255), HDAC11 (67949‐1‐lg, Proteintech, USA, dilution 1:1000,

(3) Integrating deep learning for post-translational modifications crosstalk on Hsp90 and drug bindingJ Biol ChemJuly 25, 2025Jennifer A. Heritz, Katherine A. Meluni, Sarah J. Backe, Sara J. Cayaban, Laura A. Wengert, Meik Kunz, Mark R. Woodford, Dimitra Bourboulia, Mehdi Mollapourcancer. Experimental procedures Reagents and chemicals Antibodies Antibodies for HDAC1-8 (5356, 5113, 85057, 7628, 20458, 7612, 33418) and HDAC11 (66042), GAPDH (97166), and all secondary antibodies raised in mouse

(4) Development and Characterization of the First Selective Class IIb Histone Deacetylase DegradersJournal of Medicinal ChemistryJuly 10, 2025Shiyang Zhai, Irina Honin, Linda Schäker-Hübner, Maria Hanl, Lukas Jacobi, Finn Dressler, Dominika Ewa Pieńkowska, Philipp König, Jan Gerhartz, Rabea Voget, et al.dilutions. Anti-HDAC1 (Catalog#5356S, Cell Signaling Technology, Denver, MA, USA), anti-HDAC4 (Catalog#7628S, Cell Signaling Technology, Denver, MA, USA), anti-HDAC6 (Catalog#7558S, Cell Signaling Technology,

(5) DCAF16-Based Covalent Molecular Glues for Targeted Protein Degradation of Histone DeacetylasesArch Pharm (Weinheim)July 9, 2025Tao Sun, Shiyang Zhai, Stephan Lepper, Beate König, Mateo Malenica, Irina Honin, Finn K. HansenUSA), anti‐HDAC3 (Catalog# 85057S, Cell Signaling Technology, Denver, MA, USA), anti‐HDAC4 (Catalog# 7628S, Cell Signaling Technology, Denver, MA, USA), anti‐HDAC6 (Catalog# 7558S, Cell Signaling Technology,

(6) Rewired m6A of promoter antisense RNAs in Alzheimer’s disease regulates neuronal genes in 3D nucleomeNat CommunJune 6, 2025Benxia Hu, Yuqiang Shi, Feng Xiong, Yi-Ting Chen, Xiaoyu Zhu, Elisa Carrillo, Xingzhao Wen, Nathan Drolet, Chetan Singh Rajpurohit, Xiangmin Xu, et al.anti-SYNGAP1 (1:2000; CST; #62193S), anti-MEF2C (1:1000; Abcam; #ab211493), anti-HDAC4 (1:2000; CST; #7628 T), anti-Synapsin1 (1:1000; SYSY; #106011), anti-PSD95 (1:1000; Sigma; #MAB1596), anti-GluN1 (1:1000;

(7) The SIK3-N783Y mutation is associated with the human natural short sleep traitProceedings of the National Academy of SciencesMay 13, 2025Hongmin Chen, Ye Xing, Chunyan Wan, Zheng Zhang, Zhu Shi, Yutao Liang, Chunlai Jin, Yating Chen, Xia Zhou, Junyu Xu, et al.phospho-PKA Substrate (RRXS*/T*) (#9624,CST), phospho-Ser-Pro-Pro motif [p-SPP] (#14390,CST), HDAC4(D15C3) (#7628,CST), HDAC5(B-11) (sc133106,Santa Cruz), QSK(C-2) (sc515408,Santa Cruz), Flag M2 (F1804,sigma), Phospho-MAPK

(8) Rewired m6A methylation of promoter antisense RNAs in Alzheimer’s disease regulates global gene transcription in the 3D nucleomebioRxivMarch 26, 2025Benxia Hu, Yuqiang Shi, Feng Xiong, Yi-Ting Chen, Xiaoyu Zhu, Elisa Carrillo, Xingzhao Wen, Nathan Drolet, Chetan Rajpurohit, Xiangmin Xu, et al.anti-SYNGAP1 (1:2000; CST; #62193S), anti-MEF2C (1:1000; Abcam; #ab211493), anti-HDAC4 (1:2000; CST; #7628T), anti-Synapsin1 (1:1000; SYSY; #106011), anti-PSD95 (1:1000; Sigma; #MAB1596), anti-GluN1 (1:1000;

(9) The Histone Deacetylase Activator ITSA-1 Improves the Prognosis of Cardiac Arrest Rats by Alleviating Systemic Inflammatory Responses Following Cardiopulmonary ResuscitationMediators InflammMarch 20, 2025Chenyu Zhang, Hongyan Wei, Qiang Zhang, Haohong Zhan, Yuanzheng Lu, Yujie Li, Bo Li, Wen Huang, Feng Nian, Rong Liu, et al.Bcl-2 (2870S), Bax (14796), histone H3 (9715S), HDAC1 (34589), HDAC2 (57156), HDAC3 (85057), HDAC4 (7628), HDAC6 (7612) from CST (Cell Signaling Technology, Danvers, MA, USA), and HDAC7 (ab12174), HDAC8 (ab187139),

(10) Tasquinimod promotes the sensitivity of ovarian cancer cells to cisplatin by down-regulating the HDAC4/p21 pathwayThe Korean Journal of Physiology & PharmacologyMarch 1, 2025Zhao Li, Ya-Hong Wu, Ye-Qing Guo, Xiao-Jia Min, Ying Linat 4°C. The membranes were then incubated overnight at 4°C with primary antibodies including HDAC4 (#7628, 1:1,000, CST), Bcl-2 (12789-1-AP, 1:2,000, Proteintech), cleaved-Caspase-3 (#9661, 1:1,000, CST), p21

(11) Development of the First-in-Class FEM1B-Recruiting Histone Deacetylase DegradersJournal of Medicinal ChemistryJanuary 23, 2025Felix Feller, Irina Honin, Martina Miranda, Heiko Weber, Svenja Henze, Maria Hanl, Finn K. HansenSanta Cruz Biotechnology, Dallas, TX, USA), anti-HDAC3 (Catalog# 85057S, Cell Signaling Technology), anti-HDAC4 (Catalog#7628S, Cell Signaling Technology), anti-HDAC6 (Catalog#7558S, Cell Signaling Technology), anti-HDAC8(Catalog#66042S,

(12) Combinatorial functionomics identifies HDAC6-dependent molecular vulnerability of radioresistant head and neck cancerExp Hematol OncolJanuary 12, 2025Sharon Pei Yi Chan, Celestia Pei Xuan Yeo, Boon Hao Hong, Evelyn Mui Cheng Tan, Chaw Yee Beh, Eugenia Li Ling Yeo, Dennis Jun Jie Poon, Pek Lim Chu, Khee Chee Soo, Melvin Lee Kiang Chua, et al.(Cell Signaling Technology, #5356), HDAC2 (Cell Signaling Technology, #5113), HDAC4 (Cell Signaling Technology, #7628), HDAC6 (Cell Signaling Technology, #7558), acetylated-α-tubulin Lys40 (Cell Signaling Technology, #3971),

(13) Loss of Hdac4 in osteoprogenitors impairs postnatal trabecular and cortical bone formation, resulting in a dwarfism and osteopenia phenotype in miceJournal of Biological ChemistryDecember 1, 2024YunFei Wang, Raorao Zhou, Zhengquan Dong, Wenting Wang, Li Guo, Jian Sun, Xueqin Rong, Pengcui Lito incubation with primary antibodies against Hdac4 (Abcolnal, A0239 or Cell Signaling Technology, 7628), Col1α1, ALP, osteocalcin, β-actin, and the corresponding HRP-labeled secondary antibody, protein bands

(14) Nesfatin-1 enhances vascular smooth muscle calcification through facilitating BMP-2 osteogenic signalingCell communication and signaling : CCSOctober 11, 2024Zhu XX, Meng XY, Chen G, Su JB, Fu X, Xu AJ, Liu Y, Hou XH, Qiu HB, Sun QY, et al.antibody (#14395-1-AP, Proteintech), anti-SM22α antibody (#10493-1-AP, Proteintech), anti-HDAC4 antibody (#7628S, Cell Signaling Technology), anti-p-Smad antibody (#13820, CST), anti-T-Smad antibody (#6944, CST),

(15) Selective inhibition of HDAC class IIA as therapeutic intervention for KMT2A-rearranged acute lymphoblastic leukemiaCommunications BiologyOctober 4, 2024Tamara C. A. I. Verbeek, Kirsten S. Vrenken, Susan T. C. J. M. Arentsen-Peters, Patricia Garrido Castro, Marieke van de Ven, Olaf van Tellingen, Rob Pieters, Ronald W. StamMembranes were blocked with 5% milk (Elk, Campina) and subsequently probed with antibodies against HDAC4 (#7628S, 1:2000), HDAC5 (#20458S, 1:2000)) and HDAC7 (#33418S, 1:2000) purchased from Cell Signaling; HDAC9

(16) Exploration of Hydrazide-Based HDAC8 PROTACs for the Treatment of Hematological Malignancies and Solid TumorsJournal of medicinal chemistryAugust 22, 2024Zhao C, Zhang J, Zhou H, Setroikromo R, Poelarends GJ, Dekker FJ.Cell Signaling, #5113), anti-HDAC3 (1:1000 Cell Signaling, #3949), anti-HDAC4 (1:2000 Cell Signaling, #7628), anti-HDAC6 (1:1000, Cell Signaling, #7612), anti-HDAC7 (1:1000 Cell Signaling, #33418), anti-HDAC8

(17) Negative regulation of HDAC3 transcription by histone acetyltransferase TIP60 in colon cancerGenes & GenomicsJuly 1, 2024Seong Yun Lee, Junyoung Park, Sang Beom Seo(ab2893, dilution 1:5,000) and PARP1 (ab32138, dilution 1:5,000) from Abcam (Cambridge, UK); HDAC4 (7628S; dilution 1:5,000) from Cell Signaling Technology (Danvers, MA, USA); FLAG (F3165, dilution 1:5,000),

(18) Prognostic and therapeutic model based on disulfidptosis-related genes for patients with clear cell renal cell carcinomaHeliyonJune 15, 2024Shiyong Xin, Junjie Su, Ruixin Li, Qiong Cao, Haojie Wang, Zhihao Wei, Chengliang Wang, Chengdong Zhang, Jianguo Zhang, Zheng Zhang, et al.(PVDF, Millipore). After blocking with skimmed milk powder, primary antibody (Cell Signaling Technology, 7628T, 1:1500) was added and the cells were incubated overnight at 4 °C. The following day, the primary antibody

(19) HBB contributes to individualized aconitine-induced cardiotoxicity in mice via interfering with ABHD5/AMPK/HDAC4 axisActa Pharmacologica SinicaJune 1, 2024Ya-juan Guo, Jing-jing Yao, Zhen-zhen Guo, Ming Ding, Kun-lin Zhang, Qing-hong Shen, Yu Li, Shao-fang Yu, Ting Wan, Fu-ping Xu, et al.(Cambridge, UK). Antibodies against AMPKα (5832), p-AMPKα (2535), mTOR (2983), p-mTOR (2974), and HDAC4 (7628) were obtained from Cell Signaling Technology (Boston, MA, USA). Animals All animal experiments were

(20) HDAC9‐mediated calmodulin deacetylation induces memory impairment in Alzheimer's diseaseCNS Neuroscience & TherapeuticsFebruary 7, 2024Hai‐Long Zhang, Shufen Hu, Pin Yang, Han‐Chun Long, Quan‐Hong Ma, Dong‐Min Yin, Guang‐Yin Xuanti‐SRC3 (Cell Signaling, 5765), anti‐α‐tubulin (Cell Signaling, 3873), anti‐HDAC4 (Cell Signaling, 7628), anti‐HDAC6 (Abcam, ab239362), anti‐HDAC7 (Abcam, ab166911), anti‐HDAC8 (Abcam, ab187139), anti‐HDAC9

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HDAC4 (D15C3) Rabbit mAb

HDAC4 (D15C3) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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HDAC4 (D15C3) Rabbit mAb from Cell Signaling Technology

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