HDAC4 (4A3) Mouse mAb 5392S from Cell Signaling Technology

Product Specs
ItemHDAC4 (4A3) Mouse mAb
CompanyCell Signaling Technology
Price $336.00 Inquire
Catalog Number5392S
Quantity100 µl
ApplicationsW, IP
ReactivityH, M, R, Mk
TargetHDAC4
IsotypeIgG2a
HostMouse
NCBI Gene AliasesAHO3, BDMR, HA6116, HD4, HDAC-4, HDAC-A, HDACA, NEDCHF, NEDCHID
NCBI Full Gene Namehistone deacetylase 4
Clone4A3
Molecular Weight140
ClonalityMonoclonal
Research AreaChromatin Regulation / Nuclear Function

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Cell Signaling Technology

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Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

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Website: http://www.cellsignal.com/

Website: Technical Support

(1) African swine fever virus DEAD-box helicase D1133L promotes OGG1-driven incision of genomic 8-oxoG via HDAC5 deacetylationJournal of Molecular Cell BiologyFebruary 13, 2026Jie Fan, Jifei Yang, Zhancheng Tian, Xiaoqiang Zhang, Shuxian Geng, Jianxun Luo, Istvan Boldogh, Qiaoying Zeng, Hong Yin, Guiquan Guan, et al.Cell Signaling Technology), anti-HDAC1 (PA1-860, Invitrogen), anti-HDAC2 (PA1-861, Invitrogen), and anti-HDAC4 (5392S, Cell Signaling Technology). Anti-HDAC5 (16166-1-AP), anti-HDAC6 (12834-1-AP), anti-NTHL-1 (11154-1-AP),

(2) The Molecular Mechanism Investigation of HBP-A Slows Down Meniscus Hypertrophy and Mineralisation by the Damage Mechanical ModelJournal of cellular and molecular medicineDecember 1, 2024Yang Z, Feng Y, Zhang M, Liu Y, Xiong Y, Wang X, Shi Y, Chen B, Wang Z, Ge H, et al.Sigma), Ihh (SAB2108031; Sigma), ANKH (PA5‐43526; Thermofisher, USA), ALP (ab95462; Abcam), HDAC4 (5392; CST, USA), p38 (8690; CST), Caspase3 (9662; CST). Alexa Fluor 594 secondary antibodies (33112ES60;

(3) Silencing of microRNA-106b-5p prevents doxorubicin-mediated cardiotoxicity through modulation of the PR55α/YY1/sST2 signaling axisMolecular therapy. Nucleic acidsJune 13, 2023Lax A, Soler F, Fernandez Del Palacio MJ, Pascual-Oliver S, Ballester MR, Fuster JJ, Pascual-Figal D, Asensio-Lopez MDC.(Cell Signaling Technology, 5689, 1:1,000), phospho-HDAC4 (Abcam, ab39408, 1:2,000), HDAC4 (Cell Signaling Technology, 5392, 1:1,000), YY1 (Cell Signaling Technology, 2185, 1:1,000), and sST2 (Proteintech, 11,920-1-AP, 1:1,000).

(4) ARID1A loss in pancreas leads to islet developmental defect and metabolic disturbanceiScienceJanuary 20, 2023Kuo TL, Cheng KH, Chen LT, Hung WC.RRID:AB_307272 HDAC1,Cell Signaling Technology,Cat# 5356; RRID:AB_10612242 HDAC4,Cell Signaling Technology,Cat# 5392; RRID:AB_10547753 HDAC5,Cell Signaling Technology,Cat# 2082; RRID:AB_2116626 HDAC6,Cell Signaling Technology

(5) Histone deacetylase inhibitors promote breast cancer metastasis by elevating NEDD9 expressionSignal transduction and targeted therapyJanuary 6, 2023Hu Z, Wei F, Su Y, Wang Y, Shen Y, Fang Y, Ding J, Chen Y.phosphor-FAK-Tyr397 (#8556 S), FAK (#3285 S), HDAC1 (#34589 T), HDAC2 (#5113 T), HDAC3(#3949 S), HDAC4 (#5392 S), HDAC5 (#20458 S), HDAC6 (#7558 S) were purchased from Cell Signaling Technology (Massachusetts,

(6) Quercetin alleviates diastolic dysfunction and suppresses adverse pro-hypertrophic signaling in diabetic ratsFront Endocrinol (Lausanne)December 8, 2022Linda Bartosova, Csaba Horvath, Peter Galis, Kristina Ferenczyova, Barbora Kalocayova, Adrian Szobi, Adriana Duris-Adameova, Monika Bartekova, Tomas Rajtik(ab181052, Abcam, UK), Erk5 (#12950, Cell Signaling, USA), GATA-4 (#36966, Cell Signaling, USA), HDAC4 (#5392, Cell Signaling, USA), MEF2A + MEF2C (ab197070, Abcam, UK), NFAT3 (#2183, Cell Signaling, USA), pan-Akt

(7) SIK2 inhibition enhances PARP inhibitor activity synergistically in ovarian and triple-negative breast cancersThe Journal of clinical investigationJune 1, 2022Lu Z, Mao W, Yang H, Santiago-O'Farrill JM, Rask PJ, Mondal J, Chen H, Ivan C, Liu X, Liu CG, et al.NEL 104001EA). SIK2 (catalog 6919), p-HDAC4/5/7 (catalog 3443), HDAC5 (catalog 20458), HDAC4 (catalog 5392), and actin (catalog 4967) antibodies were purchased from Cell Signaling Technology. GAPDH (catalog

(8) In Vitro Study of Licorice on IL-1β-Induced Chondrocytes and In Silico Approach for OsteoarthritisPharmaceuticals (Basel, Switzerland)December 20, 2021Ali A, Park Y, Lee J, An HJ, Jin JS, Lee JH, Chang J, Kim DK, Goo B, Park YC, et al.1:1000) and Collagen X (ab182563, 1:1000) from Abcam (Cambridge, UK). RUNX2 (#12566, 1:1000), HDAC4 (#5392, 1:1000), SOX9 (#82630, 1:1000), β-catenin (#8480, 1:1000), Lamin A/C (#4777, 1:2000), HRP linked anti-mouse

(9) Casein Kinase-2 Interacting Protein-1 Regulates Physiological Cardiac Hypertrophy via Inhibition of Histone Deacetylase 4 PhosphorylationFrontiers in physiologyJanuary 1, 2021Zhao Y, Ling S, Zhong G, Li Y, Li J, Du R, Jin X, Zhao D, Liu Z, Kan G, et al.overnight at 4°C with primary antibodies against HDAC4 (1:2,000, Cell Signaling Technology, United States, 5392S), p-HDAC4 (S632) (1:2,000, Cell Signaling Technology, United States, 3424S), p-HDAC4 (S246) (1:2,000,

(10) WWP1 Deficiency Alleviates Cardiac Remodeling Induced by Simulated MicrogravityFrontiers in cell and developmental biologyJanuary 1, 2021Zhong G, Zhao D, Li J, Liu Z, Pan J, Yuan X, Xing W, Zhao Y, Ling S, Li Y.T287, GeneTex, United States, GTX52342), HDAC4 (1:1,000, Cell Signaling Technology, United States, #5392), p-HDAC4 (1:1,000, S246, Cell Signaling Technology, United States, #3443), and GAPDH (1:2,000, Abways

(11) Frequent upregulation of G9a promotes RelB-dependent proliferation and survival in multiple myelomaExperimental Hematology & OncologyDecember 1, 2020Xi Yun Zhang, Deepa Rajagopalan, Tae-Hoon Chung, Lissa Hooi, Tan Boon Toh, Johann Shane Tian, Masturah Bte Mohd Abdul Rashid, Noor Rashidha Bte Meera Sahib, Mengjie Gu, Jhin Jieh Lim, et al.A2228), phospho-RelB (cell signaling, #5025), RelB (cell signaling, #10544), Bim (cell signaling, #5392), NF-κB2 (cell signaling, #3017), HDAC4 (cell signaling, #5392), HRP-conjugated anti-Rabbit (Cell Signaling

(12) Alteration of calcium signalling in cardiomyocyte induced by simulated microgravity and hypergravityCell proliferationMarch 1, 2020Liu C, Zhong G, Zhou Y, Yang Y, Tan Y, Li Y, Gao X, Sun W, Li J, Jin X, et al.GTX111401), p‐CaMKII (1:1000, T287, GeneTex, GTX52342), HDAC4 (1:1000, Cell Signalling Technology, #5392), p‐HDAC4 (1:1000, S632, Cell Signalling Technology, #3424), mTOR (1:1000, Cell Signalling Technology,

(13) TMCO1-mediated Ca²⁺ leak underlies osteoblast functions via CaMKII signalingNature communicationsApril 8, 2019Li J, Liu C, Li Y, Zheng Q, Xu Y, Liu B, Sun W, Li Y, Ji S, Liu M, et al.SAB2102717), RUNX2 (1:1000, Cell Signaling Technology, #8486), HDAC4 (1:1000, Cell Signaling Technology, #5392), p-HDAC4 (1:1000, S632, Cell Signaling Technology, #3424), Myc-Tag (1:1000, Cell Signaling Technology,

(14) Lens differentiation is controlled by the balance between PDGF and FGF signalingPLoS biologyFebruary 1, 2019Li H, Mao Y, Bouaziz M, Yu H, Qu X, Wang F, Feng GS, Shawber C, Zhang X.

(15) Histone deacetylase-4 and histone deacetylase-8 regulate interleukin-1β-induced cartilage catabolic degradation through MAPK/JNK and ERK pathwaysInternational journal of molecular medicineApril 1, 2018Wang P, Mao Z, Pan Q, Lu R, Huang X, Shang X, Zhang R, You H.by western blot analysis. Anti-HDAC4 antibodies were purchased from Cell Signaling Technology, Inc. (cat. no. 5392) and anti-HDAC8 antibodies were purchased from Abcam (cat. no. ab187139) and RT-qPCR, respectively as

(16) Alpha-oxoglutarate inhibits the proliferation of immortalized normal bladder epithelial cells via an epigenetic switch involving ARID1AScientific reportsMarch 14, 2018Shahid M, Gull N, Yeon A, Cho E, Bae J, Yoon HS, You S, Yoon H, Kim M, Berman BP, et al.3746; Cell Signaling Technology), ARID1A (1:1000; 12354; Cell Signaling Technology), HDAC4 (1:1000; 5392; Cell Signaling Technology), PKD (1:1000; 2052; Cell Signaling Technology), β-catenin (1:1000; 8480;

(17) Chi3l3: a potential key orchestrator of eosinophil recruitment in meningitis induced by Angiostrongylus cantonensisJournal of neuroinflammationFebruary 2, 2018Wan S, Sun X, Wu F, Yu Z, Wang L, Lin D, Li Z, Wu Z, Sun X.

(18) Myocardial CKIP-1 Overexpression Protects from Simulated Microgravity-Induced Cardiac RemodelingFrontiers in physiologyJanuary 1, 2018Ling S, Li Y, Zhong G, Zheng Y, Xu Q, Zhao D, Sun W, Jin X, Li H, Li J, et al.Specific antibodies to p-HDAC4 (Cell Signaling Technology, #3443S), HDAC4 (Cell Signaling Technology, #5392S), p-AMPKα (Cell Signaling Technology, #2531S), AMPKα (Cell Signaling Technology, #2532), p-ERK1/2 (Cell Signaling Technology

(19) Histone deacetylase adaptation in single ventricle heart disease and a young animal model of right ventricular hypertrophyPediatric ResearchOctober 1, 2017Weston W. Blakeslee, Kimberly M. Demos-Davies, Douglas D. Lemon, Katharina M. Lutter, Maria A. Cavasin, Sam Payne, Karin Nunley, Carlin S. Long, Timothy A. McKinsey, Shelley D. Miyamoto(Cell Signaling Technology, 5113), HDAC3 (Cell Signaling Technology, 3949), HDAC4 (Cell Signaling Technology, 5392), HDAC5 (Cell Signaling Technology, 2082), HDAC6 (Santa Cruz Biotechnology, Dallas, TX, USA, 11420),

(20) Chronic stress and intestinal barrier dysfunction: Glucocorticoid receptor and transcription repressor HES1 regulate tight junction protein Claudin-1 promoterScientific reportsJuly 3, 2017Zheng G, Victor Fon G, Meixner W, Creekmore A, Zong Y, K Dame M, Colacino J, Dedhia PH, Hong S, Wiley JW.

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HDAC4 (4A3) Mouse mAb

HDAC4 (4A3) Mouse mAb from Cell Signaling Technology

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Cell Signaling Technology

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HDAC4 (4A3) Mouse mAb from Cell Signaling Technology

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