Anti-CLEC1B antibodies are used in the immunodetection of the protein C-type lectin domain family 1 member B. In humans, the canonical protein has a reported length of 229 amino acid residues and a mass of 26.6 kDa. Its subcellular localization is in the membrane. Up to 2 different isoforms have been reported for this protein. It is noted to be expressed preferentially in the liver. CLEC1B is known to be involved with receptor-mediated signaling pathways. Post-translational modifications have been described, including glycosylation and phosphorylation. The CLEC1B marker can be used to identify Megakaryocytes (MK).* Synonyms for this target antigen include CLEC2, CLEC2B, PRO1384, QDED721, C-type lectin-like receptor 2, and 1810061I13Rik. CLEC1B gene orthologs have been reported in the mouse, rat, bovine and chimpanzee species.
*HuBMAP Human Reference Atlas v1.4