CLEC-2/CLEC1B Antibody AF1718 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemCLEC-2/CLEC1B Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $499.00Supplier Page View Company Product Page
Catalog NumberAF1718
ApplicationsImmunohistochemistry,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Neutralization,Immunocytochemistry,Functional Assay
HostGoat
Quantity100 ug (also 25 ug)
ReactivityHuman,Mouse,Rat
IsotypeIgG
ClonalityPolyclonal
ConcentrationLYOPH
Antibody TypePrimary Antibodies
NCBI Full Gene NameC-type lectin domain family 1 member B
NCBI Gene Aliases1810061I13Rik, CLEC2, CLEC2B, PRO1384, QDED721
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution
PurityAntigen Affinity-purified
ImmunogenMouse myeloma cell line NS0-derived recombinant human CLEC-2/CLEC1B, Gln58-Pro229, Accession # AAF36777
TargetCLEC-2/CLEC1B
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
Conjugate/TagUnconjugated

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: Detects human, mouse, and rat CLEC-2/CLEC1B in Western blots. In direct ELISAs and Western blots, less than 1% cross-reactivity with recombinant human CLEC-1 is observed.

Sizes Available: 100 ug (also 25 ug)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Identification of Podoplanin Aptamers by SELEX for Protein Detection and Inhibition of Platelet Aggregation Stimulated by C-Type Lectin-like Receptor 2Biosensors (Basel)September 27, 2024Hui-Ju Tsai, Kai-Wen Cheng, Jou-Chen Li, Tsai-Xiang Ruan, Ting-Hsin Chang, Jin-Ru Wang, Ching-Ping TsengPDPN antibody (NZ-1) was purchased from AngioBio (San Diego, CA, USA). The goat anti-CLEC-2 antibody (AF1718) and mouse anti-human CLEC-2 antibody (MAB1718) were purchased from R&D Systems (Minneapolis, MN, USA).

(2) Katacine Is a New Ligand of CLEC-2 that Acts as a Platelet AgonistThrombosis and haemostasisAugust 1, 2022Morán LA, Di Y, Sowa MA, Hermida-Nogueira L, Barrachina MN, Martin E, Clark JC, Mize TH, Eble JA, Moreira D, et al.was from Upstate Biotechnologies (Lake Placid, New York, United States); and anti-CLEC-2 antibody (AF1718) was from R&D system (Minneapolis, United States). For the HTS we have used the European Chemical Biology

(3) Candida albicans elicits protective allergic responses via platelet mediated T helper 2 and T helper 17 cell polarizationImmunityNovember 9, 2021Wu Y, Zeng Z, Guo Y, Song L, Weatherhead JE, Huang X, Zeng Y, Bimler L, Chang CY, Knight JM, et al.San Diego, CA; GPIV: 10 μg/mL ab23680, Abcam, Cambridge MA; GPVI: 10 μg/mL AF3627, CLEC2: 10 μg/mL AF1718(Tsukiji et al., 2018), R&D systems, Minneapolis, MN; TLR4: 10 μg/mL tlrl-prslps, Invivogen, San Diego,

(4) Histidine-Rich Glycoprotein Stimulates Human Neutrophil Phagocytosis and Prolongs Survival through CLEC1AJournal of immunology (Baltimore, Md. : 1950)February 15, 2021Takahashi Y, Wake H, Sakaguchi M, Yoshii Y, Teshigawara K, Wang D, Nishibori M.

(5) A pull-down and slot blot-based screening system for inhibitor compounds of the podoplanin-CLEC-2 interactionPloS oneJanuary 1, 2019Watanabe N, Kidokoro M, Suzuki Y, Tanaka M, Inoue S, Tsukamoto H, Hirayama N, Hsieh PW, Tseng CP, Nakagawa Y, et al.antibody (NZ-1, rat IgG) was purchased from Angio Bio Co. (Del Mar, CA, USA) and the anti-CLEC-2 antibody (AF1718, goat IgG) was from Novus Biologicals (Littleton, CO, USA). Horseradish peroxidase (HRP)-labeled anti-human IgG Fab2

(6) Apolipoprotein A-I Modulates Atherosclerosis Through Lymphatic Vessel-Dependent Mechanisms in MiceJournal of the American Heart AssociationSeptember 22, 2017Milasan A, Jean G, Dallaire F, Tardif JC, Merhi Y, Sorci-Thomas M, Martel C.blocked with 5% nonfat dry milk for 1 hour at room temperature. Antibodies against CLEC‐2 (R&D Systems, AF1718) and pAkt (Cell Signalling, 9275) were incubated with the membranes overnight at 4°C, and a horseradish

(7) Targeting of C-type lectin-like receptor 2 or P2Y12 for the prevention of platelet activation by immunotherapeutic CpG oligodeoxynucleotidesJournal of thrombosis and haemostasis : JTHMay 1, 2017Delierneux C, Donis N, Servais L, Wéra O, Lecut C, Vandereyken M, Musumeci L, Rahmouni S, Schneider J, Eble JA, et al.

(8) Clinicopathological correlations of podoplanin (gp38) expression in rheumatoid synovium and its potential contribution to fibroblast platelet crosstalkPloS oneJanuary 1, 2014Del Rey MJ, Faré R, Izquierdo E, Usategui A, Rodríguez-Fernández JL, Suárez-Fueyo A, Cañete JD, Pablos JL.

(9) The C-type lectin receptors CLEC-2 and Dectin-1, but not DC-SIGN, signal via a novel YXXL-dependent signaling cascadeThe Journal of biological chemistryApril 27, 2007Fuller GL, Williams JA, Tomlinson MG, Eble JA, Hanna SL, Pöhlmann S, Suzuki-Inoue K, Ozaki Y, Watson SP, Pearce AC.

(10) DC-SIGN and CLEC-2 mediate human immunodeficiency virus type 1 capture by plateletsJournal of virologySeptember 1, 2006Chaipan C, Soilleux EJ, Simpson P, Hofmann H, Gramberg T, Marzi A, Geier M, Stewart EA, Eisemann J, Steinkasserer A, et al.

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CLEC-2/CLEC1B Antibody

CLEC-2/CLEC1B Antibody

CLEC-2/CLEC1B Antibody

CLEC-2/CLEC1B Antibody

CLEC-2/CLEC1B Antibody

CLEC-2/CLEC1B Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (10)

Reviews

CLEC-2/CLEC1B Antibody from R&D Systems, a Bio-Techne Brand

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