Anti-TMCO3 antibodies are used in the immunodetection of the protein transmembrane and coiled-coil domains 3. In humans, the canonical protein has a reported length of 677 amino acid residues and a mass of 75.6 kDa. Its subcellular localization is in the membrane. Up to 3 different isoforms have been reported for this protein. It is reported to be expressed in the cornea, lens capsule and choroid-retinal pigment epithelium. A member of the Monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) protein family, TMCO3 is a suspected Na(+)/H(+) antiporter. Post-translational modifications have been described, including glycosylation. Synonyms for this target antigen include transmembrane and coiled-coil domain-containing protein 3, putative LAG1-interacting protein, and C13orf11. TMCO3 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Western Blot is a widely used application for the TMCO3 antibodies listed below. In addition, Immunohistochemistry is also a common application.