Anti-UBR1 antibodies are used in the immunodetection of the protein ubiquitin protein ligase E3 component n-recognin 1. In humans, the canonical protein has a reported length of 1749 amino acid residues and a mass of 200.2 kDa. Its subcellular localization is in the cytoplasm. Up to 2 different isoforms have been reported for this protein. It is widely expressed across many tissues, with highest levels in skeletal muscle, kidney and pancreas. A member of the UBR1 protein family, UBR1 is known to be involved with protein ubiquitination. The UBR1 gene has been associated with the disease, Johanson-Blizzard syndrome. Synonyms for this target antigen include E3a ligase, N-recognin-1, RING-type E3 ubiquitin transferase UBR1, ubiquitin ligase E3 alpha-I, ubiquitin-protein ligase E3-alpha, and E3 ubiquitin-protein ligase UBR1. UBR1 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some UBR1 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. In addition, ELISA is also a common application.