Anti-PHACTR1 antibodies are used in the immunodetection of the protein phosphatase and actin regulator 1. In humans, the canonical protein has a reported length of 580 amino acid residues and a mass of 66.3 kDa. Its subcellular localization is in the nucleus and cytoplasm. Up to 2 different isoforms have been reported for this protein. It is notably expressed in umbilical vein endothelial cells. A member of the Phosphatase and actin regulator protein family, PHACTR1 is known to bind actin monomers (G actin) and plays a role in multiple processes including the regulation of actin cytoskeleton dynamics, actin stress fibers formation, cell motility and survival, formation of tubules by endothelial cells, and regulation of PPP1CA activity. Synonyms for this target antigen include RPEL repeat containing 1. PHACTR1 gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. Some PHACTR1 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. In addition, ELISA is also a common application.