Anti-CD36 molecule antibodies are used for the immunodetection of the protein encoded by the CD36 gene. In humans, the canonical protein has a reported length of 472 amino acid residues and a mass of 53.1 kDa. Its subcellular localization is in the Golgi and cell membrane. Alternative splicing is reported to yield 4 different isoforms for this protein. A member of the CD36 protein family, it is reported to be a multifunctional glycoprotein that acts as receptor for a broad range of ligands. Post-translational modifications have been described, including O-glycosylation, N-glycosylation, ubiquitination and palmitoylation.
The CD36 molecule marker can be used to characterize Type 3 Dendritic (DC3) Cells, Early Erythroid Cells, Mid Erythroid Cells, Deep-Layer Near-Projecting Neurons, and Hypothalamus Mammillary Body Neurons.* Other names for this target antigen include CHDS7, FAT, GP3B, GP4, GPIV, PASIV, SCARB3, and BDPLT10. Gene orthologs have been identified in the mouse, rat, bovine, zebrafish, chimpanzee and chicken species. Over 1000 citations in the literature describe the use of CD36 molecule antibodies in research. Flow Cytometry is a widely used application for these antibodies. Western Blot, Immunofluorescence, and Immunohistochemistry are also common applications.
*HuBMAP Human Reference Atlas v1.4