CD36 Antibody (FA6-152)

Product Specs
ItemCD36 Antibody (FA6-152) - Azide Free
CompanyNovus Biologicals, a Bio-Techne Brand
Price $339.00Supplier Page View Company Product Page
Catalog NumberNB600-1423
Immunogen20-Weeks-old fetal erythrocytes
NCBI Gene AliasesCHDS7, GPIV, PASIV, FAT, SCARB3, GP3B, BDPLT10, GP4
Concentration0.1 mg/ml
Conjugate/TagUnconjugated
CloneFA6-152
Quantity0.05 mg
TargetCD36
FormatPBS containing 0.1% BSA
HostMouse
IsotypeIgG1
ReactivityHuman,Mouse
ClonalityMonoclonal
NCBI Full Gene NameCD36 molecule
ApplicationsWB, FCM, IA, ICC, IF, IHC, IHC-fr, IHC-p, IP, FA
Antibody TypePrimary Antibodies
Research AreaCancer, Cardiovascular Biology, Cellular Markers, Endothelial Cell Markers, Hematopoietic Stem Cell Markers, Immunology, Innate Immunity, Lipid and Metabolism, Stem Cell Markers
Molecular Weight110 kDa
StorageStore at 4C
PurityProtein G purified

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: CD36 (FA6-152)

Sizes Available: 0.05 mg

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Questions and Answers

Can this antibody be used for studying CD36 in macrophages, particularly in the context of atherosclerosis?

Yes, the CD36 Antibody (FA6-152) has been utilized in studies examining macrophage function in atherosclerosis. For instance, in a study by Liu et al. (2023), the antibody was employed in immunofluorescence to analyze CD36 expression in aortic root cryosections from mice, demonstrating its role in macrophage cholesterol transport and foam cell formation.

Is this antibody effective for use in immunohistochemistry on human tissues?

The CD36 Antibody (FA6-152) has been shown to work in immunohistochemistry applications, as indicated by its use in various studies. For example, Luo et al. (2020) utilized this antibody in their research to investigate CD36 expression in preadipocytes, suggesting its applicability in human tissue analysis.

What specific applications has this antibody been cited in, and how might that inform its use in my research?

The CD36 Antibody (FA6-152) has been cited in applications such as Western blotting, flow cytometry, immunofluorescence, and immunohistochemistry. Its versatility across these techniques allows for comprehensive studies of CD36 in various biological contexts, including inflammation and lipid metabolism, as highlighted in the literature.

Does this antibody have any known effects on cellular processes, such as inflammation or lipid accumulation?

Yes, studies have indicated that CD36 plays a significant role in inflammation and lipid metabolism. For instance, Luo et al. (2020) found that CD36 expression in preadipocytes is linked to inflammation and lysosomal dysfunction, while Liu et al. (2023) reported that modulation of CD36 expression affects cholesterol transport in macrophages, which is crucial for understanding its role in metabolic diseases.

Novus Biologicals, a Bio-Techne Brand

United States: 10771 E Easter Ave

Centennial, Colorado 80112

United States

Phone:
303-730-1950
888-506-6887

Email: novus@novusbio.com

Company Profile

Website: https://www.novusbio.com

(1) Integrin β3 Orchestrates Hepatic Steatosis via a Novel CD36‐Dependent Lipid Uptake ComplexAdvanced ScienceDecember 8, 2025Ying Zhang, Lei Dai, Zhongquan Cui, Ye Zhou, Wenyuan Dong, Hongcheng Jiang, Mengwen Wang, Xiaodan Zhong, Wei Dong, Zhang Yue, et al.protease inhibitors and 50 mM N‐ethylmaleimide. Lysates were immunoprecipitated using a CD36 antibody (Novus, NB600‐1423; 1:500 dilution) and Protein A/G Magnetic Beads (MCE, China). Each sample was split into two equal aliquots:

(2) Mfge8 promotes obesity by mediating the uptake of dietary fats and serum fatty acidsNature medicineFebruary 1, 2014Khalifeh-Soltani A, McKleroy W, Sakuma S, Cheung YY, Tharp K, Qiu Y, Turner SM, Chawla A, Stahl A, Atabai K.

(3) Placental growth factor and vascular endothelial growth factor receptor-2 in human lung developmentPediatricsJanuary 1, 0001"Janér J, Andersson S, Haglund C, Karikoski R, Lassus P."

(4) Xanthophylls are preferentially taken up compared with beta-carotene by retinal cells via a SRBI-dependent mechanismJournal of lipid researchJanuary 1, 0001"During A, Doraiswamy S, Harrison EH."

(5) CD36 plays a negative role in the regulation of lipophagy in hepatocytes through an AMPK-dependent pathwayJournal of lipid researchJanuary 1, 0001"Li Y, Yang P, Zhao L, Chen Y, Zhang X, Zeng S, Wei L, Varghese Z, Moorhead JF, Chen Y, et al."

(6) Secretory Galectin-3 promotes hepatic steatosis via regulation of the PPARγ/CD36 signaling pathwayCellular signallingJanuary 1, 0001"Yu H, Yang F, Zhong W, Jiang X, Zhang F, Ji X, Xue M, Qiu Y, Yu J, Hu X, et al."

(7) Selenoprotein K contributes to CD36 subcellular trafficking in hepatocytes by accelerating nascent COPII vesicle formation and aggravates hepatic steatosisRedox biologyJanuary 1, 0001"You M, Wu F, Gao M, Chen M, Zeng S, Zhang Y, Zhao W, Li D, Wei L, Ruan XZ, et al."slices were incubated with primary antibodies. The following primary antibodies were used: anti-CD36 (#NB600-1423, Novus Biologicals), anti-SELK (#ab121276, Abcam), anti-SEC24 (#15958-1-AP, Proteintech), anti-His-Tag

(8) Hepatocyte CD36 modulates UBQLN1-mediated proteasomal degradation of autophagic SNARE proteins contributing to septic liver injuryAutophagyJanuary 1, 0001"Li Y, Xu J, Chen W, Wang X, Zhao Z, Li Y, Zhang L, Jiao J, Yang Q, Ding Q, et al."

(9) Obesity induces preadipocyte CD36 expression promoting inflammation via the disruption of lysosomal calcium homeostasis and lysosome functionEBioMedicineJanuary 1, 0001"Luo X, Li Y, Yang P, Chen Y, Wei L, Yu T, Xia J, Ruan XZ, Zhao L, Chen Y."co-immunoprecipitation (co-IP), equal amounts of lysate proteins were incubated (4°C) with anti-mouse CD36 (Novus Cat# NB600-1423, RRID:AB_789115) overnight before protein G magnetic beads were added (Millipore) (1–3 h). Bound proteins

(10) Inhibition of fatty acid uptake by TGR5 prevents diabetic cardiomyopathyNature metabolismJanuary 1, 0001"Wang H, Wang J, Cui H, Fan C, Xue Y, Liu H, Li H, Li J, Li H, Sun Y, et al."protease inhibitors and 50 mM N-ethylmaleimide. The homogenates were immunoprecipitated with a CD36 antibody (Novus, NB600-1423; 1:500 dilution) and Pierce Protein A/G Magnetic Beads. The same sample was evenly divided into two

(11) Sulforaphane Inhibits Foam Cell Formation and Atherosclerosis via Mechanisms Involving the Modulation of Macrophage Cholesterol Transport and the Related PhenotypeNutrientsJanuary 1, 0001"Liu S, Zhang Y, Zheng X, Wang Z, Wang P, Zhang M, Shen M, Bao Y, Li D."temperature for 1 h, the sections were incubated overnight at 4 °C with primary antibodies: anti-CD36 (NB600-1423; 1:100; Novus, Minneapolis, MN, USA), anti-ABCA1 (NB400-105; 1:100; Novus), anti-ABCG1 (NB400-132; 1:100;

(12) CD36 promotes de novo lipogenesis in hepatocytes through INSIG2-dependent SREBP1 processingMolecular metabolismJanuary 1, 0001"Zeng H, Qin H, Liao M, Zheng E, Luo X, Xiao A, Li Y, Chen L, Wei L, Zhao L, et al."previously [15]. Antibody information is listed as follows: rabbit anti-CD36 (NB400-144), mouse anti-CD36 (NB600-1423), and mouse anti-SREBP1 (NB600-582) were purchased from Novus Biological (USA); rabbit anti-SREBP1 (14088-1-AP),

(13) Soluble CD36 in plasma is increased in patients with symptomatic atherosclerotic carotid plaques and is related to plaque instabilityStrokeJanuary 1, 0001"Handberg A, Skjelland M, Michelsen AE, Sagen EL, Krohg-Sørensen K, Russell D, Dahl A, Ueland T, Oie E, Aukrust P, et al."

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