Anti-catenin alpha 2 antibodies are used for the immunodetection of the protein encoded by the CTNNA2 gene. In humans, the canonical protein has a reported length of 953 amino acid residues and a mass of 105.3 kDa. Its subcellular localization is in the cell membrane, nucleus, and cytoplasm. Alternative splicing is reported to yield 6 different isoforms for this protein. It is reported to be expressed in neural tissues, with strongest expression in fetal and adult brain. A member of the Vinculin/alpha-catenin protein family, it is believed to function as a a linker between cadherin adhesion receptors and the cytoskeleton to regulate cell-cell adhesion and differentiation in the nervous system (By similarity). Other names for this target antigen include CAPR, CDCBM9, CT114, CTNR, alpha-N-catenin, and CAP-R. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Over 100 citations in the literature describe the use of catenin alpha 2 antibodies in research. Western Blot is a widely used application for these antibodies. In addition, ELISA is also a common application.