Anti-RNF169 antibodies are used in the immunodetection of the protein ring finger protein 169. In humans, the canonical protein has a reported length of 708 amino acid residues and a mass of 77.2 kDa. Its subcellular localization is in the nucleus and chromosomes. A member of the RNF169 protein family, Rnf169 is a suspected E3 ubiquitin-protein ligase that acts as a regulator of double-strand breaks (DSBs) repair following DNA damage. Post-translational modifications have been described, including phosphorylation. Synonyms for this target antigen include E3 ubiquitin-protein ligase RNF169 and RING-type E3 ubiquitin transferase RNF169. RNF169 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some Rnf169 antibodies may have been used in research and have associated citations. Immunofluorescence is a widely used application for these antibodies. Western Blot and Immunohistochemistry are also common applications.