Anti-Mac-1 antibodies are protein reagents that detect specific antigens. The Mac-1 antigen is another term for the human protein integrin subunit alpha M, encoded by the ITGAM gene. The protein is known to function in the apoptotic pathway and cell adhesion, among other biological roles. Canonically, it has an amino acid length of 1152 residues and a mass of 127.2 kilodaltons. Its subcellular localization is in the cell membrane and it is reported to be highly expressed in the monocytes and granulocytes. The Mac-1 protein is a member of the Integrin alpha chain protein family.