Anti-Synapsin I antibodies are used for the immunodetection of the protein encoded by the SYN1 gene. In humans, the canonical protein has a reported length of 705 amino acid residues and a mass of 74.1 kDa. Its subcellular localization is in the cytoplasmic vesicles and Golgi. Alternative splicing is reported to yield 2 different isoforms for this protein. A member of the Synapsin protein family, it is reported to be a neuronal phosphoprotein that coats synaptic vesicles, and binds to the cytoskeleton. Post-translational modifications have been described, including phosphorylation and glycosylation. Other names for this target antigen include EPILX1, MRX50, SYN1a, SYN1b, SYNI, synapsin-1, brain protein 4.1, and EPILX. Gene orthologs have been identified in the mouse, rat, bovine, frog and chimpanzee species. Over 760 citations in the literature describe the use of Synapsin I antibodies in research. Western Blot is a widely used application for these antibodies. ELISA, Immunofluorescence, and Immunohistochemistry are also common applications.