Anti-ALDOB antibodies are used in the immunodetection of the protein aldolase, fructose-bisphosphate B. In humans, the canonical protein has a reported length of 364 amino acid residues and a mass of 39.5 kDa. Its subcellular localization is in the cytoplasm. It is notably expressed in the small intestine, liver, kidney, and duodenum. A member of the Class I fructose-bisphosphate aldolase protein family, ALDOB is known to be involved with metabolic processes. The ALDOB marker can be used to identify Proximal Tubule Epithelial Cells.* Synonyms for this target antigen include ALDO2, fructose-bisphosphate aldolase B, aldolase 2, aldolase B, fructose-bisphosphatase, aldolase B, fructose-bisphosphate, and ALDB. ALDOB gene orthologs have been reported in the mouse, rat, bovine, chimpanzee and chicken species.
*HuBMAP Human Reference Atlas v1.4