Anti-GRK2 antibodies are used in the immunodetection of the protein G protein-coupled receptor kinase 2. In humans, the canonical protein has a reported length of 689 amino acid residues and a mass of 79.6 kDa. Its subcellular localization is in the cell membrane and cytoplasm. It is reported to be expressed in peripheral blood leukocytes. A member of the AGC Ser/Thr protein kinase protein family, GRK2 is known to be involved with GPCR signaling pathways and cardiac tissue development. Synonyms for this target antigen include BARK1, BETA-ARK1, beta-adrenergic receptor kinase 1, adrenergic beta receptor kinase 1, beta-ARK-1, and ADRBK1. GRK2 gene orthologs have been reported in the mouse, rat, bovine, chimpanzee and chicken species.