PRMT8 is a symbol for the gene, Protein arginine methyltransferase 8, in humans. Other names include: Protein arginine N-methyltransferase 8; Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 4; Protein arginine N-methyltransferase 8 ; HRMT1L3; HRMT1L4. The encoded protein is an enzyme with an amino acid length of 394 and a mass of 45.3 kDa. Other isoforms may exist. PRMT8 is a member of the Class I-like SAM-binding methyltransferase superfamily, Protein arginine N-methyltransferase family, PRMT8 subfamily. This gene shares homology with other species, including: Mouse, Rat, Zebrafish, Frog, Chicken.