Anti-CYP2R1 antibodies are used in the immunodetection of the protein cytochrome P450 family 2 subfamily R member 1. In humans, the canonical protein has a reported length of 501 amino acid residues and a mass of 57.4 kDa. Its subcellular localization is in the ER. It is notably widely expressed in many tissue types. A member of the Cytochrome P450 protein family, CYP2R1 is a cytochrome P450 monooxygenase involved in activation of vitamin D precursors. The CYP2R1 gene has been associated with the disease, Rickets vitamin D-dependent. Synonyms for this target antigen include cytochrome P450 2R1, cytochrome P450, family 2, R1, cytochrome P450, family 2, subfamily R, polypeptide 1, and vitamin D 25-hydroxylase. CYP2R1 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of CYP2R1 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.