Anti-BATF antibodies are used in the immunodetection of the protein basic leucine zipper ATF-like transcription factor. In humans, the canonical protein has a reported length of 125 amino acid residues and a mass of 14.1 kDa. Its subcellular localization is in the nucleus and cytoplasm. It is reported to be expressed at highest levels in the lung, and at lower levels in the placenta, liver, kidney, spleen, and peripheral blood. A member of the BZIP protein family, BATF is known to be involved with DNA damage pathways and hematopoietic stem cell differentiation. Post-translational modifications have been described, including phosphorylation. The BATF marker can be used to identify Naive Regulatory T Cells.* Synonyms for this target antigen include SFA-2, SFA2, basic leucine zipper transcriptional factor ATF-like, B-cell-activating transcription factor, and BATF1. BATF gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.
*HuBMAP Human Reference Atlas v1.4