BATF (D7C5) Rabbit mAb 8638S from Cell Signaling Technology

Product Specs
ItemBATF (D7C5) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number8638S
Quantity100 µl
ApplicationsW, IP, FC-FP
ReactivityH, M
TargetBATF
HostRabbit
NCBI Gene AliasesB-ATF, BATF1, SFA-2, SFA2
ClonalityMonoclonal
NCBI Full Gene Namebasic leucine zipper ATF-like transcription factor
Research AreaImmunology and Inflammation
IsotypeIgG
CloneD7C5
Molecular Weight15

Questions and Answers

Can this BATF antibody be used in studies related to autoimmune diseases?

Yes, the BATF (D7C5) Rabbit mAb has been utilized in research related to autoimmune diseases. For instance, in the study by Chuang et al. (2018), BATF was shown to play a role in the transcriptional regulation of IL-17A, which is critical in the pathogenesis of autoimmune conditions.

Is this antibody effective for detecting BATF in human samples?

The BATF (D7C5) Rabbit mAb is reactive to human samples, as indicated by its use in various studies, including those examining the role of BATF in hepatocellular carcinoma (Liu et al., 2022) and its involvement in immune responses.

How has this antibody been applied in immunological research?

This antibody has been employed in immunofluorescence and Western blotting to study BATF's role in T cell differentiation and function, as demonstrated in multiple studies, including those investigating its interaction with other transcription factors in T cells (Chuang et al., 2023; Welsh et al., 2024).

What experimental techniques can I use this antibody with?

The BATF (D7C5) Rabbit mAb is suitable for various applications, including Western blotting, flow cytometry, and immunoprecipitation, as evidenced by its use in multiple publications that detail these methodologies (Chuang et al., 2018; Zhang et al., 2023).

Cell Signaling Technology

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Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) ITK-targeted immune remodeling enhanced the efficacy of anti-CD19 CAR-T cell therapyCell Death DiscoveryMarch 6, 2026Zhenjun Li, Liangcheng Lv, Xiaoyu Yao, Zhiwei Feng, Yan Xie, Kecheng Li, Feifei Qi, Mei Yang, Jingwen Wang, Tao Pan, et al.Phospho-Ser1248-PLCγ1 (#8713), PLCγ1 (#5690), TCF1 (#2203), NR4A (#3960), NFAT1 (#5861), Tox (#36778), BATF (#8638), TNF-a (#3707), LAG3 (#15372) and GAPDH (#5174) were provided by Cell Signaling Technology (Danvers,

(2) OSMR coordinates a self-perpetuating circuit linking chemoresistance and neutrophil-driven immunosuppression in gastric cancerNeoplasiaFebruary 6, 2026Dan Wei, Jiang Chen, Feihu Bai, Donglin Li, Jie Liu, Hongjia Dou, Yan Lei, Yongzhen Zhang, Bo Zhang, Ying Pang, et al.#20356-1-AP), GATA3 (CST, #5852), p-SMAD1/5 (CST, #9516), SMAD5 (CST, #12534), PD-L1 (CST, #13684), BATF (CST, #8638), IL-31 (abcam, #ab62579)), which were diluted in accordance with the manufacturer's instructions. After

(3) The transcription factor BATF pioneers the differentiation program of effector CD8+ T cells through the interaction with IRF4Cell ReportsAugust 26, 2025Sotaro Fujisawa, Yamato Tanabe, Arisa Hojo, Ryotaro Shiga, Junko Kurachi, Miki Koura, Toshikatsu Tamai, Yusuke Miyanari, E. John Wherry, Makoto KurachiNormal rabbit IgG,Invitrogen,Cat# 02-6102; RRID:AB_2532938 Anti-BATF (clone D7C5),Cell Signaling Technology,Cat# 8638; RRID:AB_11141425 Anti-IRF4 (clone D9P5H),Cell Signaling Technology,Cat# 15106; RRID:AB_2798709 Ultra-LEAF

(4) The Nuclear Receptor NR1B1/RARα Arrests the Differentiation of Anti‐Tumor Effector Cytotoxic T CellsAdvanced ScienceMarch 11, 2025Patrick Niekamp, Ryun Hee Kim, Adithyan Jayaraman, Nils Klement, Raymond Kostlan, Chang H. KimAPC anti‐mouse Ki‐67 (BioLegend Cat# 652406, RRID:AB_2561930), Anti‐mouse/human BATF (Cell Signaling Technology Cat# 8638, RRID:AB_11141425), APC anti‐mouse CD3 (BioLegend Cat# 100236, RRID:AB_2561456), ANTI‐FLAG (Sigma Aldrich

(5) The CD8+ T cell tolerance checkpoint triggers a distinct differentiation state defined by protein translation defectsImmunityJune 1, 2024Willem Van Der Byl, Simone Nüssing, Timothy J. Peters, Antonio Ahn, Hanjie Li, Guy Ledergor, Eyal David, Andrew S. Koh, Mayura V. Wagle, Christian Deo T. Deguit, et al.12-9858-82; RRID:AB_10852721 "Rabbit anti-BATF (unconjugated), Clone D7C5",Cell Signaling Technology,Cat# 8638S; RRID:AB_11141425 "Mouse anti-Bcl6 (AlexaFluor 647-conjugated), Clone K112-91",BD Biosciences,Cat#

(6) Shared and distinct interactions of type 1 and type 2 Epstein-Barr Nuclear Antigen 2 with the human genomeBMC GenomicsMarch 12, 2024Kenyatta C. M. F. Viel, Sreeja Parameswaran, Omer A. Donmez, Carmy R. Forney, Matthew R. Hass, Cailing Yin, Sydney H. Jones, Hayley K. Prosser, Arame A. Diouf, Olivia E. Gittens, et al.Intercept Blocking Buffer for 1 h at room temperature. The primary antibody was diluted (BATF, CST 8638, 1:1000; EBF1, Santa Cruz sc-137065, 1:500; EBNA2, [PE2] Abcam ab90543, 1:1000; JUNB, Active Motif 39,549,

(7) Transcriptional Heterogeneity Overcomes Super-Enhancer Disrupting Drug Combinations in Multiple MyelomaBlood Cancer DiscoveryJanuary 8, 2024Seth J. Welsh, Benjamin G. Barwick, Erin W. Meermeier, Daniel L. Riggs, Chang-Xin Shi, Yuan Xiao Zhu, Meaghen E. Sharik, Megan T. Du, Leslie D Abrego Abrego Rocha, Victoria M. Garbitt, et al.Analyzer. Western Blots All antibodies for western blots were purchased online. BATF (D7C5, Cell Signaling 8638, used at 1:1,000), BATF2 (PCRP-BATF2-2B9, Developmental Studies Hybridoma Bank, University of Iowa;

(8) DUSP8 induces TGF-β-stimulated IL-9 transcription and Th9-mediated allergic inflammation by promoting nuclear export of Pur-αThe Journal of clinical investigationNovember 1, 2023Chuang HC, Hsueh CH, Hsu PM, Tsai CY, Shih YC, Chiu HY, Chen YM, Yu WK, Chen MH, Tan TH.were incubated with antibodies against DUSP8 (1:200), Pur-α (1:200, clone 1C10, Abcepta), BATF (1:200, 8638, Cell Signaling Technology), PU.1 (1:500, MA5-15064, Invitrogen), or IRF-4 (1:100, 4964, Cell Signaling Technology

(9) BATF relieves hepatic steatosis by inhibiting PD1 and promoting energy metabolismeLifeSeptember 15, 2023Zhang Z, Liao Q, Pan T, Yu L, Luo Z, Su S, Liu S, Hou M, Li Y, Damba T, et al.incubated with primary antibody overnight at 4 °C. The primary antibodies included a BATF antibody (8638 S, Cell Signaling Technology, USA), anti-β-actin (GB11001, Servicebio, China), and β-tublin (15115,

(10) CD8(+) T cell-intrinsic IL-6 signaling promotes resistance to anti-PD-L1 immunotherapyCell reports. MedicineJanuary 17, 2023Huseni MA, Wang L, Klementowicz JE, Yuen K, Breart B, Orr C, Liu LF, Li Y, Gupta V, Li C, et al.AC-15),Sigma-Aldrich,Cat#A3854; RRID:AB_262011 Rabbit anti-BATF (clone D7C5),Cell Signaling Technology,Cat#8638; RRID:AB_11141425 Hamster anti-mouse CD3e (clone 145-2C11),BD Biosciences,Cat#550275; RRID:AB_393572 Hamster

(11) Long Noncoding RNA BCYRN1 Recruits BATF to Promote TM4SF1 Upregulation and Enhance HCC Cell Proliferation and InvasionDisease MarkersJune 11, 2022Ya Liu, Meng-jie Liu, Min Jiao, Li-li Jiang, Xiao Fu, Wen-juan Wangpolyclonal anti-MMP2 (1 : 1000, ab97779, Abcam, Cambridge, MA, USA), rabbit monoclonal anti-BATF (1 : 1000, #8638, Cell Signaling Technology, Danvers, MA), rat anti-TM4SF1 (1 : 2000, ab113504, Abcam, Cambridge, MA,

(12) A systematic comparison of FOSL1, FOSL2 and BATF-mediated transcriptional regulation during early human Th17 differentiationNucleic acids researchMay 20, 2022Shetty A, Tripathi SK, Junttila S, Buchacher T, Biradar R, Bhosale SD, Envall T, Laiho A, Moulder R, Rasool O, et al.Biotechnology, Cat no. sc-28310), FOSL2 (Cell Signaling Tech, Cat. no. 19967) or BATF (Cell Signaling, Cat. no. 8638) antibody was pre-incubated with magnetic beads for crosslinking (Dynal Biotech/Invitrogen, Cat. no.

(13) Protein kinase Cδ is essential for the IgG response against T-cell-independent type 2 antigens and commensal bacteriaeLifeOctober 25, 2021Fukao S, Haniuda K, Tamaki H, Kitamura D.ab227383,WB (1/5000) Antibody,BATF (D7C5) Rabbit mAb (Rabbit monoclonal),Cell Signaling Technology,Cat# 8638,WB (1/2000) Antibody,Phospho-PKCdelta (Tyr311) Antibody (Rabbit polyclonal),Cell Signaling Technology,Cat#

(14) BATF regulates progenitor to cytolytic effector CD8(+) T cell transition during chronic viral infectionNature immunologyAugust 1, 2021Chen Y, Zander RA, Wu X, Schauder DM, Kasmani MY, Shen J, Zheng S, Burns R, Taparowsky EJ, Cui W.anti-TCF-1 (C63D9, rabbit mAb, Cell Signaling, 2203S, 1:400), anti-BATF (D7C5, rabbit mAb, Cell Signaling, 8638, 1:400), goat anti-rabbit IgG (H+L) cross-adsorbed secondary antibody, Alexa Fluor 647 (Thermo Fisher,

(15) Activation-induced deaminase is critical for the establishment of DNA methylation patterns prior to the germinal center reactionNucleic acids researchMay 21, 2021Català-Moll F, Ferreté-Bonastre AG, Li T, Weichenhan D, Lutsik P, Ciudad L, Álvarez-Prado ÁF, Rodríguez-Ubreva J, Klemann C, Speckmann C, et al.protein A, according to manufacturer's instructions (Diagenode, Liege, Belgium). Anti-BATF antibody (#8638) and corresponding rabbit IgG (#2729) were both obtained from Cell Signaling. Protein binding was analyzed

(16) BATF Regulates T Regulatory Cell Functional Specification and Fitness of Triglyceride Metabolism in Restraining Allergic ResponsesJournal of immunology (Baltimore, Md. : 1950)May 1, 2021Xu C, Fu Y, Liu S, Trittipo J, Lu X, Qi R, Du H, Yan C, Zhang C, Wan J, et al.RT-PCR Immunoblots were performed as described previously (71), using the following antibodies: BATF (Cat#8638; Cell Signaling Technology), p-LKB1S428 (Cat#3482; Cell Signaling Technology), IRF4 (Cat#15106; Cell Signaling Technology

(17) CD4⁺ T Cell Help Is Required for the Formation of a Cytolytic CD8⁺ T Cell Subset that Protects against Chronic Infection and CancerImmunityDecember 17, 2019Zander R, Schauder D, Xin G, Nguyen C, Wu X, Zajac A, Cui W.RRID:AB_2536538 Anti-TCF-1 (C63D9),Cell Signaling,Cat#2203S; RRID:AB_2199302 Anti-mouse BATF (D7C5),Cell Signaling,Cat#8638S; RRID:AB_11141425 Anti-mouse Eomes (Dan11mag),Invitrogen,Cat#25-4875-82; RRID:AB_2573454 Anti-mouse

(18) GLK-IKKβ signaling induces dimerization and translocation of the AhR-RORγt complex in IL-17A induction and autoimmune diseaseScience advancesSeptember 1, 2018Chuang HC, Tsai CY, Hsueh CH, Tan TH.(Thr256; #2939), anti-SGK1 (clone D27C11), anti-histone 3 (#9715S), anti-IRF4 (#4964S), and anti-BATF (#8638S) antibodies were purchased from Cell Signaling Technology. Anti-STAT3 (#06-596) and anti-RORγt (clone

(19) Targeting the HTLV-I-Regulated BATF3/IRF4 Transcriptional Network in Adult T Cell Leukemia/LymphomaCancer CellAugust 1, 2018Masao Nakagawa et al.ab32072, RRID:AB_731658" BATF (D7C5) Rabbit mAb #8638,Cell Signaling,"Cell Signaling Technology Cat# 8638S, RRID:AB_11141425" Rabbit-polyclonal-HBZ serum,"Arnold et al., 2008",N/A Polyclonal Sheep-Human BATF3

(20) Histone demethylase KDM4A and KDM4B expression in granulosa cells from women undergoing in vitro fertilizationJournal of Assisted Reproduction and GeneticsJune 1, 2018Adam J. Krieg, Sarah R. Mullinax, Frances Grimstad, Kaitlin Marquis, Elizabeth Constance, Yan Hong, Sacha A. Krieg, Katherine F. Robyhematoxylin counterstain [39]. Rabbit monoclonal KDM4A (#5328, Cell Signaling) and KDM4B antibody (#8638, Cell Signaling) were each used at dilutions of 1:50 and 1:100, respectively. Rabbit monoclonal IgG

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BATF (D7C5) Rabbit mAb

BATF (D7C5) Rabbit mAb from Cell Signaling Technology

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Questions and Answers

Cell Signaling Technology

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BATF (D7C5) Rabbit mAb from Cell Signaling Technology

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