Anti-CARTPT antibodies are used in the immunodetection of the protein CART prepropeptide. In humans, the canonical protein has a reported length of 116 amino acid residues and a mass of 12.8 kDa. It has been described to be a secreted protein. It is notably expressed in the hypothalamus, cerebral cortex, and adrenal gland. A member of the CART protein family, CARTPT is known to be involved with cell to cell signaling and chemical synaptic transmission.
The CARTPT marker can be used to identify Amygdala Excitatory Neurons, Thalamic Excitatory Neurons, and Dorsal Excitatory Neurons.* Synonyms for this target antigen include CART and cocaine- and amphetamine-regulated transcript protein. CARTPT gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. A number of CARTPT antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.
*HuBMAP Human Reference Atlas v1.4