Anti-ZNF746 antibodies are used in the immunodetection of the protein zinc finger protein 746. In humans, the canonical protein has a reported length of 644 amino acid residues and a mass of 69.1 kDa. Its subcellular localization is in the nucleus and cytoplasm. Up to 3 different isoforms have been reported for this protein. It is notably expressed in many tissues, such as the adrenal gland and placenta. A member of the Krueppel C2H2-type zinc-finger protein family, ZNF746 is reported to be a transcription repressor that specifically binds to the 5'-TATTTT[T/G]-3' consensus sequence on promoters and repress transcription of PGC-1-alpha (PPARGC1A), thereby playing a role in regulation of neuron death. Synonyms for this target antigen include parkin-interacting substrate and parkin-interacting sustrate. ZNF746 gene orthologs have been reported in the mouse, rat, bovine and chimpanzee species. A number of ZNF746 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. In addition, Immunohistochemistry is also a common application.