Anti-DLL4 antibodies are used in the immunodetection of the protein delta like canonical Notch ligand 4. In humans, the canonical protein has a reported length of 685 amino acid residues and a mass of 74.6 kDa. Its subcellular localization is in the cell membrane. It is reported to be expressed in vascular endothelium. DLL4 is reported to be involved in Notch signaling pathway as Notch ligand. Post-translational modifications have been described, including glycosylation. The DLL4 gene has been associated with the disease, Adams-Oliver syndrome. Synonyms for this target antigen include delta4, hdelta2, delta-like protein 4, delta 4, delta ligand 4, delta-like 4 homolog, delta-like 4 protein, and AOS6. DLL4 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Over 460 citations in the literature describe the use of DLL4 antibodies in research. ELISA is a widely used application for these antibodies. In addition, Flow Cytometry is also a common application.