Fig 1: Effects of CYP2J2 or TERFENADONE on Dll4 and Jagged1 expression in a hypoxia model. HRVECs were exposed to hypoxia for 24 h and then transfected with pcDNA3.1(+)-GFP or pcDNA3.1(+)-CYP2J2, or induced by Terfenadone for 24 h. (a) western blot analysis of CYP2J2, Dll4, and Jagged1 expression. (b-d) mRNA levels of CYP2J2, Dll4, and jagged1 in different groups. **P < 0.01 vs. Normal; ##P < 0.01 vs. Hypoxia+pcDNA3.1(+)-GFP; && P < 0.01 vs. Hypoxia