Anti-KCNH8 antibodies are used in the immunodetection of the protein potassium voltage-gated channel subfamily H member 8. In humans, the canonical protein has a reported length of 1107 amino acid residues and a mass of 123.8 kDa. Its subcellular localization is in the membrane. Up to 2 different isoforms have been reported for this protein. It is notably expressed in the nervous system. A member of the Potassium channel protein family, KCNH8 is known to be involved with potassium ion transport and the transport of ions. Post-translational modifications have been described, including glycosylation.
The KCNH8 marker can be used to identify Thalamic Excitatory Neurons.* Synonyms for this target antigen include ether-a-go-go-like potassium channel 1, ether-a-go-go-like potassium channel 3, hElk1, potassium channel, voltage gated eag related subfamily H, member 8, and ELK channel 3. KCNH8 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Western Blot is the most common application for the KCNH8 antibodies listed below. ELISA and Immunohistochemistry are also common applications.
*HuBMAP Human Reference Atlas v1.4